Author: ifonge

The Food and Drug Administration on Friday rejected — again — an experimental treatment for advanced skin cancer developed by Replimune Group.  Replimune’s treatment, an engineered virus designed to rev up the immune system against melanoma, has been a flashpoint in a simmering debate over shifting standards at the agency. The drug was initially rejected in July, just two months after Vinay Prasad was appointed the FDA’s head of biologics. As an academic oncologist, Prasad criticized regulators for approving drugs with limited data, and the Replimune decision was viewed as a possible sign of the stricter stance he might take…

Along with Zohran Mamdani’s historic victory in last month’s elections, New York City also approved three housing-related ballot proposal. Together, these will make it somewhat easier to adjust land-use rules to allow for new housing development, by reducing the City Council’s ability to block zoning changes. I am glad the proposals passed, for reasons similar to those laid out by Michael Kinnucan. While zoning changes are not a sufficient solution to the city’s housing problems, they are helpful — and more important, they are a necessary condition for a bigger program of public investment in housing. Support for the proposals was…

The Justice Department said Friday that it would move forward on a proposed $68 million settlement with a Texas land developer it had accused of preying on Hispanic residents, despite a judge’s concerns that the agreement did not do enough to help victims. During a hearing, U.S. District Judge Alfred H. Bennett questioned why the settlement had no compensation for those who were harmed and grilled a federal prosecutor over $20 million devoted to police and immigration enforcement. He said he was uncomfortable with the provision because the Justice Department’s lawsuit against Colony Ridge, which has massive subdivisions north of…

State wildlife officials have finally come up with a theory to explain where a giant, highly destructive rodent that’s been terrorizing California came from: Oregon.Nutria, a creature with the body of a small beaver, webbed feet like a platypus, and the tail of a rat, reappeared in the state’s wetlands a few years ago, nearly four decades after it was considered eradicated.California has been battling the rodent ever since, and recent research by wildlife officials suggests the rodents’ sudden return may have been intentional.The study, released Tuesday by the California Department of Fish and Wildlife, found that the state’s nutria…

Yup, that’s right. I pulled the trigger and have bought Crimson Desert, the highly anticipated, highly topical game that’s recently been released. Hyped as the “it can do anything” type of game, this is an action-adventure open-world game from South Korean developer Pearl Abyss, the devs behind the MMO Black Desert Online. There’s a lot to unpack here, so let’s dive into it. First, some housekeeping: I’m playing on a base PS5 in quality mode, targeting 30 frames per second. I have no problem with that; frames aren’t something that really bothers me. I prefer the more cinematic look of…

Small League Team — Safe PicksWK: Kusal Mendis, Haseebullah Khan BAT: Babar Azam, Mohammad Naeem, Abdullah Shafique ALL: Iftikhar Ahmed, Sikandar Raza BOWL: Shaheen Afridi, Sufiyan Muqeem, Nahid Rana, Mustafizur Rahman Captain: Babar Azam | Vice-Captain: Kusal Mendis  Make smarter fantasy choices today by reviewing KAR vs PES and LAH vs ISL Dream11 predictions along with useful tips. Grand League Team — High Risk, High RewardWK: Kusal Mendis BAT: Babar Azam, Mohammad Naeem, Abdul Samad ALL: Iftikhar Ahmed, Sikandar Raza, Michael Bracewell BOWL: Shaheen Afridi, Haris Rauf, Sufiyan Muqeem, Nahid Rana Captain: Kusal Mendis | Vice-Captain: Shaheen Afridi

The most wonderful time of the golf season continues into the weekend as the beauty of April surrounds Augusta National Golf Club with some of the best weather featured at “a tradition unlike any other” in years. The 2026 Masters is off and running with another star-studded affair, and history is on the line over the final 36 holes as defending champion Rory McIlroy has opened up a six-shot lead, the largest ever entering the weekend at this prestigious tournament.McIlroy is seeking to become the first golfer since Tiger Woods (2001-02) to win consecutive Masters and the fourth ever to…

LONDON — British authorities arrested a man from Sudan on Friday on suspicion of endangering life after four migrants died trying to board an inflatable boat to cross the English Channel.Two men and two women died and 38 others were rescued Thursday after being swept away in strong currents at a French beach where they had been attempting to launch for the perilous crossing to Britain.The 27-year-old suspect was one of more than 70 other migrants who continued the journey and he was arrested at a migrant processing center on England’s southeast coast under a new border and immigration law…

Arsenal boss Mikel Arteta will hope to see his side build on Tuesday’s narrow win over Sporting CP when they face Bournemouth in the Premier League on Saturday.  The Gunners currently sit nine points clear at the top of the table, although second-placed Manchester City do have a game-in-hand. Arteta has guided his seen his side finish second in each of the past three campaigns, and the Spaniard will be desperate to go one better this time around. Ahead of the visit of the Cherries, though, it is emerging that one member of Arteta’s squad is keen to stay put…

Let’s start with a rare ray of good news. In Wisconsin, liberal judge Chris Taylor absolutely boat-raced her Republican opponent, Maria Lazar. The victory gives Democrats a 5–2 advantage on the Wisconsin state Supreme Court and ensures that Democrats will control the court during the 2028 presidential election cycle.People might remember last year’s Wisconsin Supreme Court race—the one that Elon Musk tried to buy, the one that became the most expensive judicial election in history. The GOP candidate lost anyway, and Democrats took control of the court for the first time in 15 years.This year, the stakes weren’t as stark.…